T-cell attack & Cancer evasion

This video was made thanks to the 3D Cell Explorer from Nanolive SA. Here we can see 4 big pancreatic cancer cells that are mostly static and the smaller T-cells crawling and moving very quickly trying to find cancer cells…

T-cell attack & Cancer evasion

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This video was made thanks to the 3D Cell Explorer from Nanolive SA.

Here we can see 4 big pancreatic cancer cells that are mostly static and the smaller T-cells crawling and moving very quickly trying to find cancer cells to kill them.
Despite the best efforts of the T-cells the cancer cells evade them by not being recognized.

At the 40 seconds mark we can see one of the cancer cells starting mitosis (cell division). We can appreciate the nucleoli disappearing when prophase occurs, followed by the alignment of the condensed chromosomes at the midline of the cell, and at minute 1:09 we can see anaphase followed by telophase and then the separation happens. Amazingly, we can see T-cells recognizing the daughter cells and start to pull! With more research we can hopefully find out why they did this and how to turn them into better fighters.

Technology:
Nanolive imaging, Switzerland.
The 3D Cell Explorer is a high speed, high resolution and non-invasive live cell imaging microscope that can look deep inside biological systems. This allows you to record stunning 3D images of entire cells in just seconds and with a higher resolution than any conventional microscope on the market.

For more information, visit www.nanolive.ch

Video kindly provided by the Champalimaud Foundation in Portugal. With special thanks to Joao Martins Research Technician At Champalimaud Centre for the Unknown.

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